Broccoli may be good for the gut

Image credit: Bigstock

Image credit: Bigstock

Problem

Can everyday foods help prevent inflammatory diseases such as colitis and Crohn's?

Findings

Researchers found that when mice ate broccoli, they were better able to tolerate digestive issues that can lead to serious disease.

Impact

Broccoli and other cruciferous vegetables, such as brussels sprouts and cauliflower, maintain a healthy balance in gut flora by strengthening the intestinal barrier that keeps out toxins and harmful microorganisms. Compounds in these vegetables may help prevent diseases such as heart disease, various cancers, and Crohn's disease.

Research Area: Integrated Health Solutions

Research Credit

Team

  • Gary Perdew, Troy D. Hubbard, Iain Murray, Robert Nichols, Kaitlyn Cassel, Michael Podolsky, Guray Kuzu, Yuan Tian, Philip Smith, Mary Kennett, and Andrew Patterson

Competitive Funding

  • National Science Foundation; Penn State College of Agricultural Sciences; Huck Institutes of the Life Sciences

Federal and State Appropriations

  • USDA NIFA Hatch Project PEN04608, Accession #1010032

Published Research

Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner.

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Office for Research and Graduate Education

Address

217 Agricultural Administration Building
University Park, PA 16802-2600