Edward G Dudley, Ph.D.

Edward G Dudley, Ph.D.

  • Director of E. coli Reference Center
  • Professor of Food Science
427 Rodney A. Erickson Food Science Building
University Park, PA 16802

Areas of Expertise

  • Microbiology
  • Microbial pathogens
  • Molecular microbiology
  • Microbial genomics
  • Food Safety
  • Food Microbiology

Education

  • Postdoctoral research, University of Maryland School of Medicine
  • Ph.D., University of Wisconsin Madison, Bacteriology, 2000
  • M.S., University of Wisconsin Madison, Food Science, 1994
  • B.S., Penn State University, Microbiology, 1991

Publications

Corrigendum to "A Comparative Study on Antimicrobial Resistance in Escherichia coli Isolated from Channel Catfish and Related Freshwater Fish Species" [J. Food Protect. 87(1) (2023) 100192
J.MILK.FOOD TECHNOL., Soku, Yesutor K., Mohamed, Abdelrahman, Samuel, Temesgen, Dessai, Uday, Walls, Isabel, Rockwell, Catherine, Fortenberry, Gamola, Berutti, Tracy, Nieves-Miranda, Sharon, Nawrocki, Erin M., Fu, Yezhi, Dudley, Edward, Mamber, Stephen W., Hicks, John, 2024

A Comparative Study on Antimicrobial Resistance in Escherichia coli Isolated from Channel Catfish and Related Freshwater Fish Species
J.MILK.FOOD TECHNOL., Soku, Yesutor K., Mohamed, Abdelrahman, Samuel, Temesgen, Dessai, Uday, Walls, Isabel, Rockwell, Catherine, Fortenberry, Gamola, Berutti, Tracy, Nieves-Miranda, Sharon, Nawrocki, Erin M., Fu, Yezhi, Dudley, Edward, Mamber, Stephen W., Hicks, John, Beck, Benjamin H., 2024

Genomic characterization of Listeria monocytogenes and Listeria innocua isolated from milk and dairy samples in Ethiopia
BMC Genomic Data, Wei, Xiaoyuan, Hassen, Anwar, McWilliams, Karen, Pietrzen, Karen, Chung, Taejung, Acevedo, Marysabel, Chandross-Cohen, Tyler, Dudley, Edward, Vipham, Jessie, Mamo, Hassen, Tessema, Tesfaye, Zewdu, Ashagrie, Kovac, Jasna, 2024

Exploring Antimicrobial Resistance Profiles of E. coli Isolates in Dairy Cattle: A Baseline Study across Dairy Farms with Varied Husbandry Practices in Puerto Rico
Microorganisms, Malavez, Yadira, Nieves-Miranda, Sharon M., Loperena Gonzalez, Paola N., Padin-Lopez, Adrian F., Xiaoli, Lingzi, Dudley, Edward G., 2023

High resistance of fluoroquinolone and macrolide reported in avian pathogenic Escherichia coli isolates from the humid subtropical regions of Pakistan
Journal of Global Antimicrobial Resistance, Jalil, Amna, Masood, Saleha, Ain, Quratul, Andleeb, Saadia, Dudley, Edward G., Adnan, Fazal, 2023

Whole-Genome Subtyping Reveals Population Structure and Host Adaptation of Salmonella Typhimurium from Wild Birds
Journal of Clinical Microbiology, Fu, Yezhi, M’ikanatha, Nkuchia M., Dudley, Edward G., 2023

Global Distribution of O Serotypes and Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Collected from the Blood of Patients with Bacteremia Across Multiple Surveillance Studies
Clinical Infectious Diseases, Weerdenburg, Eveline, Davies, Todd, Morrow, Brian, Zomer, Aldert L., Hermans, Peter, Go, Oscar, Spiessens, Bart, van den Hoven, Thijs, van Geet, Gunter, Aitabi, Moussa, Debroy, Chitrita, Dudley, Edward G., Bonten, Marc, Poolman, Jan, Geurtsen, Jeroen, 2023

Comparison of genotypic and phenotypic predictions for heavy metal resistance in Salmonella enterica and Escherichia coli
American Journal of Undergraduate Research, Riverez-Diaz, Jeevan, Phillippi, Haley, Mbodo, Nyduta, Nawrocki, Erin, Dudley, Edward, 2022

Virulence Potential of Escherichia coli Isolates from a Beef Farm in Puerto Rico
Genome Announcements, Malavez, Yadira, Loperena-Gonzalez, Paola N., Nieves-Miranda, Sharon M., Vazquez-Rodriguez, Enilanice, Centeno-Velez, Carlos N., Xiaoli, Lingzi, Dudley, Edward G., 2022

Increase in quinolone resistance among salmonella isolates from retail meat samples is driven by Salmonella enteritidis and Salmonella infantis
Journal of Global Antimicrobial Resistance, Yin, Xin, Dudley, Edward G., Pinto, Casey N., M'ikanatha, Nkuchia M., 2022

Fluoroquinolone sales in food animals and quinolone resistance in non-typhoidal Salmonella from retail meats: United States, 2009–2018
Journal of Global Antimicrobial Resistance, Yin, Xin, Dudley, Edward G., Pinto, Casey N., M'ikanatha, Nkuchia M., 2022

Genomic analysis of Salmonella Typhimurium from humans and food sources accurately predicts phenotypic multi-drug resistance
Food Microbiology, Yin, Xin, Fu, Yezhi, Tate, Heather, Pinto, Casey, Dudley, Edward G., M'ikanatha, Nkuchia M., 2022

Salmonella enterica Serovar Typhimurium Isolates from Wild Birds in the United States Represent Distinct Lineages Defined by Bird Type
Applied and Environmental Microbiology, Fu, Yezhi, M'ikanatha, Nkuchia M., Lorch, Jeffrey M., Blehert, David S., Berlowski-Zier, Brenda, Whitehouse, Chris A., Li, Shaoting, Deng, Xiangyu, Smith, Jared C., Shariat, Nikki W., Nawrocki, Erin M., Dudley, Edward G., 2022

Mcc1229, an Stx2a-Amplifying Microcin, Is Produced In Vivo and Requires CirA for Activity
Infection and Immunity, Nawrocki, Erin M., Hutchins, Laura E., Eaton, Kathryn A., Dudley, Edward G., 2022

Evidence for common ancestry and microevolution of passerine-adapted Salmonella enterica serovar Typhimurium in the UK and USA
Microbial genomics, Fu, Yezhi, Smith, Jared C., Shariat, Nikki W., M’ikanatha, Nkuchia M., Dudley, Edward G., 2022

Mcc1229, an Stx2a-amplifying microcin, is produced in vivo and requires CirA for activity.
Infection and immunity, Nawrocki, E, Hutchins, L, Eaton, K, Dudley, Edward, 2021

Antimicrobial-coated films as food packaging: A review
Comprehensive Reviews in Food Science and Food Safety, Fu, Yezhi, Dudley, Edward G., 2021

O-serotype distribution of Escherichia coli bloodstream infection isolates in critically ill patients in The Netherlands
Vaccine, Verboom, D. M., Varkila, M. R.J., Morrow, B., Davies, T., Ibarra de Palacios, P., Poolman, J., Hermans, P. W.M., Dudley, E. G., Roberts, E., Cremer, O. L., Bonten, M. J.M., 2021

A Targeted Sequencing Assay for Serotyping Escherichia coli Using AgriSeq Technology
Frontiers in Microbiology, Elder, Jacob R., Fratamico, Pina M., Liu, Yanhong, Needleman, David S., Bagi, Lori, Tebbs, Robert, Allred, Adam, Siddavatam, Prasad, Suren, Haktan, Gujjula, Krishna Reddy, DebRoy, Chitrita, Dudley, Edward G., Yan, Xianghe, 2021

CRISPR typing in Salmonella, Shariat, Nikki, Dudley, Edward, 2021

CRISPR Typing of Salmonella Isolates, Shariat, Nikki, Dudley, Edward, 2021

Low occurrence of multi-antimicrobial and heavy metal resistance in Salmonella enterica from wild birds in the United States
Environmental Microbiology, Fu, Yezhi, M'ikanatha, Nkuchia M., Whitehouse, Chris A., Tate, Heather, Ottesen, Andrea, Lorch, Jeffrey M., Blehert, David S., Berlowski-Zier, Brenda, Dudley, Edward G., 2021

The Intriguing Interaction of Escherichia coli with the Host Environment and Innovative Strategies To Interfere with Colonization: a Summary of the 2019 E. coli and the Mucosal Immune System Meeting
Applied and Environmental Microbiology, Cox, Eric, Aloulou, Meryem, Fleckenstein, James M., Schäffer, Christina, Sjöling, Åsa, Schüller, Stephanie, Hanevik, Kurt, Devriendt, Bert, Zhang, Weiping, Svennerholm, Ann Mari, Dudley, Edward G., 2020

A Toxic Environment: a Growing Understanding of How Microbial Communities Affect Escherichia coli O157:H7 Shiga Toxin Expression
Applied and Environmental Microbiology, Nawrocki, Erin M., Mosso, Hillary M., Dudley, Edward G., 2020

Whole Genome Sequencing: The Impact on Foodborne Outbreak Investigations, Kovac, Jasna, Dudley, Edward G., Nawrocki, Erin M., Yan, Runan, Chung, Taejung, 2020

Novel Effective Bacillus cereus Group Species “Bacillus clarus” Is Represented by Antibiotic-Producing Strain ATCC 21929 Isolated from Soil
mSphere, Acevedo, Marysabel Méndez, Méndez Acevedo, M, Carroll, Laura M., Mukherjee, M, Mills, E, Xiaoli, Lingzi, Dudley, Edward G., Kovac, Jasna, 2020

Draft genome sequences of isolates of diverse host origin from the E. coli reference center at penn state university
Genome Announcements, Lacher, David W., Mammel, Mark K., Gangiredla, Jayanthi, Gebru, Solomon T., Barnaba, Tammy J., Majowicz, Sydney A., Dudley, Edward G., 2020

Whole-genome sequences of salmonella isolates from an ecological wastewater treatment system
Genome Announcements, Connolly, Charles J., Kaminsky, Laura, Pinto, Gabriella N., Sinclair, Priscilla C., Bajracharya, Gyasu, Yan, Runan, Nawrocki, Erin M., Dudley, Edward G., Kovaca, Jasna, 2020

A putative microcin amplifies Shiga toxin 2a production of Escherichia coli O157:H7
Journal of Bacteriology, Mosso, Hillary M., Xiaoli, Lingzi, Banerjee, Kakolie, Hoffmann, Maria, Yao, Kuan, Dudley, Edward G., 2019

Detection of CTX-M-1 extended-spectrum beta-lactamase among ceftiofur-resistant Salmonella enterica clinical isolates of poultry
Journal of Veterinary Diagnostic Investigation, Denagamage, T, Wallner-Pendleton, Eva, Jayarao, Bhushan, Xiaoli, L, Dudley, Edward G., Wolfgang, D, Kariyawasam, S, 2019

Use of whole genome sequencing in surveillance for antimicrobial-resistant Shigella sonnei infections acquired from domestic and international sources
Microbial genomics, Abelman, Rebecca L., M'ikanatha, Nkuchia M., Figler, Hillary M., Dudley, Edward G., 2019

Retrospective whole-genome sequencing analysis distinguished PFGE and drug-resistance-matched retail meat and clinical Salmonella isolates
Journal of General Microbiology, Keefer, Andrea B., Xiaoli, Lingzi, M’ikanatha, Nkuchia M., Yao, Kuan, Hoffmann, Maria, Dudley, Edward G., 2019

Whole-genome sequences of Escherichia coli isolates from cocoa beans imported from bolivia
Genome Announcements, Nwanosike, Hephzibah, Chung, Taejung, Xiaoli, Lingzi, Condello, Megan, Dudley, Edward G., Kovac, Jasna, 2019

Whole-genome sequencing reveals resistome of highly drug-resistant retail meat and human Salmonella Dublin
Zoonoses and Public Health, Eyler, Andrea B., M'ikanatha, Nkuchia M., Xiaoli, Lingzi, Dudley, Edward G., 2019

Non-pathogenic escherichia coli enhance Stx2a production of E. coli O157:H7 through both bamA-dependent and independent mechanisms
Frontiers in Microbiology, Xiaoli, Lingzi, Figler, Hillary M., Banerjee, Kakolie Goswami, Hayes, Christopher S., Dudley, Edward G., 2018

Critical synergistic concentration of lecithin phospholipids improves the antimicrobial activity of eugenol against Escherichia coli
Applied and Environmental Microbiology, Zhang, Haoshu, Dudley, Edward G., Harte, Federico, 2017

Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA
PLoS One, DiMarzio, Michael, Rusconi, Brigida, Yennawar, Neela H., Eppinger, Mark, Patterson, Andrew D., Dudley, Edward G., 2017

Critical concentration of lecithin enhances the antimicrobial activity of eugenol against Escherichia coli
Applied and Environmental Microbiology, Zhang, Haoshu, Dudley, Edward G., Davidson, P. Michael, Harte, Federico, 2017

Prevalence and phylogenetic characterization of Escherichia coli and hygiene indicator bacteria isolated from leafy green produce, beef, and pork obtained from farmers' markets in Pennsylvania
J.MILK.FOOD TECHNOL., Scheinberg, Joshua A., Dudley, Edward G., Campbell, Jonathan, Roberts, Beth, DiMarzio, Michael, DebRoy, Chitrita, Cutter, Catherine N., 2017

Draft genome sequence of Bacillus velezensis GF610, a producer of potent anti- Listeria agents
Genome Announcements, Gerst, Michelle M., Dudley, Edward G., Xiaoli, Lingzi, Yousef, Ahmed E., 2017

Draft genome sequence of Brevibacillus laterosporus OSY-I1, a strain that produces brevibacillin, which combats drug-resistant Gram-positive bacteria
Genome Announcements, Yang, Xu, Huang, En, Yesil, Mustafa, Xiaoli, Lingzi, Dudley, Edward G., Yousef, Ahmed E., 2017

Whole-genome sequence of Escherichia coli serotype O157:H7 strain PA20
Genome Announcements, Uhlich, Gaylen A., Paoli, George C., Zhang, Xinmin, Dudley, Edward G., Figler, Hillary M., Cottrell, Bryan J., Andreozzi, Elisa, 2017

A quantitative enzyme-linked immuosorbant assay for Shiga-toxin 2 requiring only commercially available components
Advance Food Technology Nutrition Science Open Journal, Xiaoli, Lingzi, Dudley, Edward, 2017

Longitudinal Monitoring of Successive Commercial Layer Flocks for Salmonella enterica Serovar Enteritidis
Foodborne Pathogens and Disease, Denagamage, T, Patterson, Paul, Wallner-Pendleton, Eva, Trampel, D, Shariat, N, Dudley, Edward G., Jayarao, Bhushan M., Kariyawasam, S, 2016

Commercially Available Rapid Methods for Detection of Selected Food-borne Pathogens
Critical Reviews in Food Science and Nutrition, Valderrama, Wladir B., Dudley, Edward G., Doores, Stephanie, Cutter, Catherine N., 2016

Prevalence and Spatial Distribution of Salmonella Infections in the Pennsylvania Raccoon (Procyon lotor)
Zoonoses and Public Health, Very, K, Kirchner, M, Shariat, N, Cottrell, W, Sandt, C, Dudley, E. G., Kariyawasam, S, Jayarao, B. M., 2016

The interplay of Escherichia coli O157:H7 and commensal E. coli: The importance of strain-level identification
Expert Review of Gastroenterology and Hepatology, Figler, Hillary M., Dudley, Edward G., 2016

CRISPR-Based Typing and Next-Generation Tracking Technologies
Annual review of food science and technology, Barrangou, Rodolphe, Dudley, Edward G., 2016

Diversity of secretion systems associated with virulence characteristics of the classical bordetellae
Journal of General Microbiology, Park, Jihye, Zhang, Ying, Chen, Chun, Dudley, Edward G., Harvill, Eric T., 2015

A newly discovered Bordetella species carries a transcriptionally active CRISPR-Cas with a small Cas9 endonuclease
BMC Genomics, Ivanov, Yury V., Shariat, Nikki, Register, Karen B., Linz, Bodo, Rivera, Israel, Hu, Kai, Dudley, Edward G., Harvill, Eric T., 2015

Escherichia coli O157: H7 strains harbor at least three distinct sequence types of Shiga toxin 2a-converting phages
BMC Genomics, Yin, Shuang, Rusconi, Brigida, Sanjar, Fatemeh, Goswami, Kakolie, Xiaoli, Lingzi, Eppinger, Mark, Dudley, Edward G., 2015

Diversity of CRISPR loci and virulence genes in pathogenic Escherichia coli isolates from various sources
International Journal of Food Microbiology, Jiang, Yun, Yin, Shuang, Dudley, Edward G., Cutter, Catherine N., 2015

Coculture of Escherichia coli O157:H7 with a nonpathogenic E. coli strain increases toxin production and virulence in a germfree mouse model
Infection and Immunity, Goswami, Kakolie, Chen, Chun, Xiaoli, Lingzi, Eaton, Kathryn A., Dudley, Edward G., 2015

Characterization and evolution of Salmonella CRISPR-Cas systems
Journal of General Microbiology, Shariat, Nikki, Timme, Ruth E., Pettengill, James B., Barrangou, Rodolphe, Dudley, Edward G., 2015

Comparative analysis of subtyping methods against a whole-genome-sequencing standard for Salmonella enterica serotype Enteritidis
Journal of Clinical Microbiology, Deng, Xiangyu, Shariat, Nikki, Driebe, Elizabeth M., Roe, Chandler C., Tolar, Beth, Trees, Eija, Keim, Paul, Zhang, Wei, Dudley, Edward G., Fields, Patricia I., Engelthaler, David M., 2015

Complete nucleotide sequence of pRS218, a large virulent plasmid that augment pathogenic potential of meningitis-associated Escherichia coli strain RS218
BMC Microbiology, Wijetunge, D, Karunathilake, E, Chaudhari, A, Katani, R, Dudley, Edward, Kapur, V, DebRoy, C, Kariyawasam, S, 2015

Genome sequence of Escherichia coli O157: H7 strain 2886-75, associated with the first reported case of human infection in the United States
Genome Announcements, Sanjar, Fatemeh, Hazen, Tracy H., Shah, Sadiq M., Koenig, Sara S.K., Agrawal, Sonia, Daugherty, Sean, Sadzewicz, Lisa, Tallon, Luke J., Mammel, Mark K., Feng, Peter, Soderlund, Robert, Tarr, Phillip I., DebRoy, Chitrita, Dudley, Edward G., Cebula, Thomas A., Ravel, Jacques, Fraser, Claire M., Rasko, David A., Eppinger, Mark, 2014

Ceramide trihexoside bottom spot as a receptor to detect Shiga toxin 2 from STEC
August 2014 newsletter of Matreya, LLC, Xiaoli, L, Goswami, K, Dudley, Edward, 2014

CRISPRs: molecular markers for tracking antibiotic resistant strains of Salmonella enterica
Winter 2014 newsletter of the Alliance for the Prudent Use of Antibiotics, Dudley, Edward, 2014

Complete nucleotide sequence of pRS218, a large virulence plasmid, that augments pathogenic potential of meningitis-associated Escherichia coli strain RS218
BMC Microbiology, Wijetunge, Dona Saumya S., Karunathilake, Kurundu Hewage Eranda M., Chaudhari, Atul, Katani, Robab, Dudley, Edward G., Kapur, Vivek, Debroy, Chitrita, Kariyawasam, Subhashinie, 2014

CRISPRs: Molecular Signatures Used for Pathogen Subtyping
Applied and Environmental Microbiology, Shariat, Nikki, Dudley, Edward G., 2014